Article
Behavioral and respiratory characteristics during sleep in neonatal DBA/2J and A/J mice.
Brain research - 19 Nov 2008
Balbir Alexander, Lande Boris, Fitzgerald Robert S, Polotsky Vsevolod, Mitzner Wayne, Shirahata Machiko
Abstract excerpt
The ventilatory response to hypoxia depends on the carotid body function and sleep-wake states. Therefore, the response must be measured in a consistent sleep-wake state. In mice, EMG with behavioral indices (coordinated movements, CMs; myoclonic twitches, MTs) has been used to assess sleep-wake states. However, in neonatal mice EMG instrumentation could induce stress, altering their behavior and ventilation....
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