Article
Disease-modifying capability of murine Flt3-ligand DCs in experimental autoimmune encephalomyelitis.
Journal of leukocyte biology - 1 Dec 2007
Papenfuss Tracey L, Kithcart Aaron P, Powell Nicole D, McClain Melanie A, Gienapp Ingrid E, Shawler Todd M, Whitacre Caroline C
Abstract excerpt
Dendritic cells (DCs) bridge the innate and adaptive immune response, are uniquely capable of priming naïve T cells, and play a critical role in the initiation and regulation of autoimmune and immune-mediated disease. At present, in vivo expansion of DC populations is accomplished primarily throu...
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