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Article

Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements.

Nucleic acids research - 1 Jan 2007

Coolen Marcel W, Statham Aaron L, Gardiner-Garden Margaret, Clark Susan J

Abstract excerpt

CpG methylation is a key component of the epigenome architecture that is associated with changes in gene expression without a change to the DNA sequence. Since the first reports on deregulation of DNA methylation, in diseases such as cancer, and the initiation of the Human Epigenome Project, an i...

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Identifiers

PMID: 17855397
DOI: 10.1093/nar/gkm662
PMCID: PMC2094090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17855397-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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