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Article

A pipeline for the quantitative analysis of CG dinucleotide methylation using mass spectrometry.

Bioinformatics (Oxford, England) - 1 Sept 2009

Thompson Reid F, Suzuki Masako, Lau Kevin W, Greally John M

Abstract excerpt

MOTIVATION: DNA cytosine methylation is an important epigenetic regulator, critical for mammalian development and the control of gene expression. Numerous techniques using either restriction enzyme or affinity-based approaches have been developed to interrogate cytosine methylation status genome-wide, however these assays must be validated by a more quantitative approach, such as MALDI-TOF mass spectrometry of...

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PMID: 19561019
DOI: 10.1093/bioinformatics/btp382
PMCID: PMC2800352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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