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Article

Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas.

Clinical endocrinology - 1 Feb 2008

Tadjine Mimi, Lampron Antoine, Ouadi Lydia, Bourdeau Isabelle

Abstract excerpt

OBJECTIVE: Molecular alterations remain largely unknown in most sporadic adrenocortical tumours and hyperplasias. In our previous work, we demonstrated the differential expression of several Wnt/beta-catenin signalling-related genes implicated in ACTH-independent macronodular adrenal hyperplasias (AIMAH). To better understand the role of Wnt/beta-catenin signalling in adrenocortical tumours, we performed...

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Share to Adrenal and Paraganglionic Tumors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17854394
DOI: 10.1111/j.1365-2265.2007.03033.x

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