Article
Investigation of BRAF and CTNNB1 activating mutations in adrenocortical tumors.
Journal of endocrinological investigation - 1 Jul 2009
Masi G, Lavezzo E, Iacobone M, Favia G, Palù G, Barzon L
Abstract excerpt
BACKGROUND: Activating mutations of the BRAF oncogene play a central role in the development of various cancer types, but their role in human adrenocortical tumors is unknown. At variance, activating mutations of another oncogene, CTNNB1, which encodes beta-catenin, have been shown to be common e...
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