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Article

Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50.

The EMBO journal - 17 Oct 2007

Eimer Stefan, Gottschalk Alexander, Hengartner Michael, Horvitz H Robert, Richmond Janet, Schafer William R, Bessereau Jean-Louis

Abstract excerpt

Nicotinic acetylcholine receptors (AChRs) are pentameric ligand-gated ion channels that mediate fast synaptic transmission at the neuromuscular junction (NMJ). After assembly in the endoplasmic reticulum (ER), AChRs must be transported to the plasma membrane through the secretory apparatus. Little is known about specific molecules that mediate this transport. Here we identify a gene that is required for...

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Share to Caenorhabditis elegans Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Nicotinic

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Source

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Identifiers

PMID: 17853888
DOI: 10.1038/sj.emboj.7601858
PMCID: PMC2034668

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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