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Article

Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers

12 Sept 2007

Abstract excerpt

INTRODUCTION: Age is one of the most important risk factors for human malignancies, including breast cancer; in addition, age at diagnosis has been shown to be an independent indicator of breast cancer prognosis. Except for inherited forms of breast cancer, however, there is little genetic or epigenetic understanding of the biological basis linking aging with sporadic breast cancer incidence and its clinical...

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PMID: 17850661
DOI: 10.1186/bcr1765

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