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Article

HLA in Portuguese systemic lupus erythematosus patients and their relation to clinical features.

Annals of the New York Academy of Sciences - 1 Sept 2009

Vasconcelos Carlos, Carvalho Claudia, Leal Bárbara, Pereira Clara, Bettencourt Andreia, Costa Paulo P, Marinho António, Barbosa Paulo, Almeida Isabel, Farinha Fátima, Mendonça Teresa, Correia João Araujo, Mendonça Denisa, Martins Berta

Abstract excerpt

Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease translating the different genetic and environmental factors involved. Polymorphisms at several loci, including the major histocompatibility complex (MHC), have been associated worldwide with SLE, although inconsistencies exist among these studies mainly due to genetic heterogeneity between populations and sample characteristics. The aim of...

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PMID: 19758202
DOI: 10.1111/j.1749-6632.2009.04873.x

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