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Article

An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction.

American journal of human genetics - 1 Oct 2007

Shen Gong-Qing, Li Lin, Girelli Domenico, Seidelmann Sara B, Rao Shaoqi, Fan Chun, Park Jeong Euy, Xi Quansheng, Li Jing, Hu Ying, Olivieri Oliviero, Marchant Kandice, Barnard John, Corrocher Roberto, Elston Robert, Cassano June, Henderson Susan, Hazen Stanley L, Plow Edward F, Topol Eric J, Wang Qing K

Abstract excerpt

Our previous genomewide linkage scan of 428 nuclear families (GeneQuest) identified a significant genetic susceptibility locus for premature myocardial infarction (MI) on chromosome 1p34-36. We analyzed candidate genes in the locus with a population-based association study involving probands with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17847002
DOI: 10.1086/521581
PMCID: PMC2227927

Genes

CAD
LRP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17847002-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction.PMID 17847002Read ↗

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