Article
Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis.
American journal of human genetics - 1 Feb 2004
Wang Qing, Rao Shaoqi, Shen Gong-Qing, Li Lin, Moliterno David J, Newby L Kristin, Rogers William J, Cannata Ruth, Zirzow Erich, Elston Robert C, Topol Eric J
Abstract excerpt
The most frequent causes of death and disability in the Western world are atherosclerotic coronary artery disease (CAD) and acute myocardial infarction (MI). This common disease is thought to have a polygenic basis with a complex interaction with environmental factors. Here, we report results of a genomewide search for susceptibility genes for MI in a well-characterized U.S. cohort consisting of 1,613 individuals...
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