Article
Immunological roles of Pasteurella multocida toxin (PMT) using a PMT mutant strain.
Journal of microbiology (Seoul, Korea) - 1 Aug 2007
Kim Tae Jung, Toan Nguyen Tat, Jang Eun Jin, Jung Bock Gie, Lee Jae Il, Lee Bong Joo
Abstract excerpt
The immunological role of the Pasteurella multocida toxin (PMT) in mice was examined using a PMT mutant strain. After a nasal inoculation, the mutant strain failed to induce interstitial pneumonia. Moreover, PMT had no significant effect on the populations of CD4+, CD8+, CD3+, and CD19+ immunocytes in blood or on the populations of CD4+ and CD8+ splenocytes (P<0.01). However, there was a significant increase in...
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