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Article

Comparison of bone marrow-derived and mucosal mast cells in controlling intramacrophage Francisella tularensis replication.

Experimental biology and medicine (Maywood, N.J.) - 1 Jun 2012

Hunter Colleen, Rodriguez Annette, Yu Jieh-Juen, Chambers James, Guentzel M Neal, Arulanandam Bernard

Abstract excerpt

Although the importance of mast cells (MCs) in response to allergens has been characterized extensively, the contribution of these cells in host defense against bacterial pathogens is not well understood. Previously, we have demonstrated that the release of interleukin-4 by bone marrow-derived MCs inhibits intramacrophage replication of Francisella tularensis live vaccine strain (LVS). Because pneumonic tularemia...

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Identifiers

PMID: 22688822
DOI: 10.1258/ebm.2012.011389
PMCID: PMC4135514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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