Article
Vaccine potential of an attenuated Pasteurella multocida that expresses only the N-terminal truncated fragment of P. multocida toxin in pigs.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire - 1 Jan 2012
Kim Taejung, Son Changho, Lee Jaeil, Kim Kwanghyun
Abstract excerpt
Previously we described the development of an attenuated Pasteurella multocida mutant that expresses only the N-terminal truncated fragment of P. multocida toxin (N-PMT) and its protective effects in a mouse model. This paper details our evaluation of the vaccine potential of this mutant strain in pigs. Pigs vaccinated with the mutant showed significantly higher rates of antibody induction and lower nasal conchal...
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