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Article

Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1.

Proceedings of the National Academy of Sciences of the United States of America - 18 Sept 2007

Magnúsdóttir Erna, Kalachikov Sergey, Mizukoshi Koji, Savitsky David, Ishida-Yamamoto Akemi, Panteleyev Andrey A, Calame Kathryn

Abstract excerpt

The cornified layer is a compacted lattice of lipid-embedded corneocytes that provides an organism's barrier to the external environment. Cornification is the final differentiative step for epidermal keratinocytes and involves dramatic cell condensation before death. Using conditional gene deletion in mice, we identified the transcriptional repressor Blimp-1 (B lymphocyte-induced maturation protein-1) as an...

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Source

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Identifiers

PMID: 17846422
DOI: 10.1073/pnas.0707323104
PMCID: PMC1986600

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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