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Article

Transcriptional profiling of epidermal differentiation

6 Jul 2006

Abstract excerpt

In epidermal differentiation basal keratinocytes detach from the basement membrane, stop proliferating, and express a new set of structural proteins and enzymes, which results in an impermeable protein/lipid barrier that protects us. To define the transcriptional changes essential for this process, we purified large quantities of basal and suprabasal cells from human epidermis, using the expression of beta4...

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PMID: 16822832
DOI: 10.1152/physiolgenomics.00031.2006

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