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Article

A homolog of male sex-determining factor SRY cooperates with a transposon-derived CENP-B protein to control sex-specific directed recombination.

Proceedings of the National Academy of Sciences of the United States of America - 15 Nov 2011

Matsuda Emiko, Sugioka-Sugiyama Rie, Mizuguchi Takeshi, Mehta Sameet, Cui Bowen, Grewal Shiv I S

Abstract excerpt

Schizosaccharomyces pombe cells switch mating type by replacing genetic information at the expressed mat1 locus with sequences copied from mat2-P or mat3-M silent donor loci. The choice of donor locus is dictated by cell type, such that mat2 is the preferred donor in M cells and mat3 is the preferred donor in P cells. Donor choice involves a recombination-promoting complex (RPC) containing Swi2 and Swi5. In P...

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Identifiers

PMID: 22042869
DOI: 10.1073/pnas.1109988108
PMCID: PMC3219157

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A homolog of male sex-determining factor SRY cooperates with a transposon-derived CENP-B protein to control sex-specific directed recombination.PMID 22042869Read ↗

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