Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clostridium perfringens Enterotoxin as a Novel-Targeted Therapeutic for Brain Metastasis

1 Sept 2007

Abstract excerpt

Brain metastasis is the most commonly occurring intracranial tumor whose incidence seems to be increasing. With standard therapy, the average survival time of patients is approximately 8 months, and treatment often leads to neurologic dysfunction in long-term survivors, emphasizing the need for novel therapeutics. Clostridium perfringens enterotoxin (CPE) has recently been shown to rapidly and specifically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Metastases and Treatment
Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17804705
DOI: 10.1158/0008-5472.can-07-1314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clostridium perfringens Enterotoxin as a Novel-Targeted Therapeutic for Brain MetastasisPMID 17804705Read ↗

Targeting claudin-overexpressing thyroid and lung cancer by modified Clostridium perfringens enterotoxin.Semantic proximity Read ↗

Tissue distribution and safety evaluation of a claudin-targeting molecule, the C-terminal fragment of Clostridium perfringens enterotoxin.Semantic proximity Read ↗

Human Claudin-8 and -14 Are Receptors Capable of Conveying the Cytotoxic Effects of Clostridium perfringens EnterotoxinSemantic proximity Read ↗

Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexesSemantic proximity Read ↗

Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gutSemantic proximity Read ↗

Claudin‐4‐targeted therapy using <i>Clostridium perfringens</i> enterotoxin for prostate cancerSemantic proximity Read ↗

Identification of a Claudin-4 Residue Important for Mediating the Host Cell Binding and Action of <i>Clostridium perfringens</i> EnterotoxinSemantic proximity Read ↗

Inhibition of EGFR/ErbB does not protect against <i>C. difficile</i> toxin BSemantic proximity Read ↗

The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer.Semantic proximity Read ↗

Claudin-4 Overexpression in Epithelial Ovarian Cancer Is Associated with Hypomethylation and Is a Potential Target for Modulation of Tight Junction Barrier Function Using a C-Terminal Fragment of Clostridium perfringens EnterotoxinSemantic proximity Read ↗

Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics.Semantic proximity Read ↗

Metastasis of Breast Tumor Cells to Brain Is Suppressed by Phenethyl Isothiocyanate in a Novel In Vivo Metastasis ModelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.