Article
Persistent T-cell activation and clinical correlations in patients with ANCA-associated systemic vasculitis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jul 2006
Marinaki Smaragdi, Kälsch Anna-Isabelle, Grimminger Peter, Breedijk Annette, Birck Rainer, Schmitt Wilhelm H, Weiss Christel, van der Woude Fokko J, Yard Benito A
Abstract excerpt
BACKGROUND: Although in antineutrophil cytoplasmic autoantibodies (ANCA)-associated systemic vasculitis (AASV) patients, activation of T-cells has been described, persistence of these alterations has not been well characterized. This study was conducted to define persistent T-cell activation (PTA) in AASV patients and to assess whether this correlates with disease activity, disease severity, age or therapy....
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