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Article

Sterol pathway in yeast. Identification and properties of mutant strains defective in mevalonate diphosphate decarboxylase and farnesyl diphosphate synthetase.

Lipids - 1 Aug 1991

Chambon C, Ladeveze V, Servouse M, Blanchard L, Javelot C, Vladescu B, Karst F

Abstract excerpt

Yeast mutant strains auxotrophic for ergosterol and blocked in mevalonate diphosphate decarboxylase (erg19) and farnesyl diphosphate (FPP) synthetase (erg20) were isolated. The main feature of the mutants blocked in FPP synthetase is their ability to excrete prenyl alcohols, such as geraniol and...

Topics

Acyclic Monoterpenes
Carboxy-Lyases
Dimethylallyltranstransferase
Ergosterol
Farnesol
Gene Expression
Genes, Fungal
Mutation
Saccharomyces cerevisiae
Sterols
Terpenes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1779710
DOI: 10.1007/BF02536428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1779710-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Sterol pathway in yeast. Identification and properties of mutant strains defective in mevalonate diphosphate decarboxylase and farnesyl diphosphate synthetase.PMID 1779710Read ↗

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