Isolation and properties of yeast mutants affected in farnesyl diphosphate synthetase.

doi:10.1007/BF00321113

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Article

Isolation and properties of yeast mutants affected in farnesyl diphosphate synthetase.

Current genetics - 1 Jul 1990

Chambon C, Ladeveze V, Oulmouden A, Servouse M, Karst F

Abstract excerpt

Two yeast mutant strains auxotrophic for ergosterol and blocked in farnesyl diphosphate synthetase (EC 2.5.1.1) were isolated. Genetic analysis has shown that these mutant strains carry additional mutations in the ergosterol pathway besides erg20-1 and erg20-2 which affect FPP synthetase. The nov...

Topics

Acyclic Monoterpenes
Cell Membrane Permeability
Dimethylallyltranstransferase
Ergosterol
Farnesol
Genes, Fungal
Genetic Complementation Test
Mevalonic Acid
Mutation
Phenotype
Restriction Mapping
Saccharomyces cerevisiae
Terpenes

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