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Article

Isolation and properties of yeast mutants affected in farnesyl diphosphate synthetase.

Current genetics - 1 Jul 1990

Chambon C, Ladeveze V, Oulmouden A, Servouse M, Karst F

Abstract excerpt

Two yeast mutant strains auxotrophic for ergosterol and blocked in farnesyl diphosphate synthetase (EC 2.5.1.1) were isolated. Genetic analysis has shown that these mutant strains carry additional mutations in the ergosterol pathway besides erg20-1 and erg20-2 which affect FPP synthetase. The novel feature of these mutants is their ability to excrete prenyl alcohols (farnesol and geraniol). As geraniol is toxic...

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PMID: 2245473
DOI: 10.1007/BF00321113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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