Article
Sterols in erg mutants of Phycomyces: metabolic pathways and physiological effects.
Steroids - 1 Apr 2002
Barrero Alejandro F, Oltra J Enrique, Robinson John, Burke Patricia V, Jiménez David, Oliver Eulalia
Abstract excerpt
Phycomyces is a fungal producer of beta-carotene and other beneficial metabolites. Several erg mutants of Phycomyces, originally selected to study the effects of membrane alteration on physiological responses, have now been used to gain information about sterol biosynthesis in filamentous fungi. One mutant, H23, and its progeny were found to be blocked at episterol C-5 dehydrogenase and did not produce ergosterol...
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