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Article

Left-Sided microsatellite unstable colorectal cancers show less frequent methylation of hMLH1 and CpG island methylator phenotype than right-sided ones.

Journal of surgical oncology - 1 Dec 2007

Tanaka Junichiro, Watanabe Toshiaki, Kanazawa Takamitsu, Tada Tomohiro, Kazama Yoshihiro, Tanaka Toshiaki, Nagawa Hirokazu

Abstract excerpt

CONDENSED ABSTRACT: We compared the methylation status of several loci between right-sided and left-sided colorectal cancers (CRCs). To the best of our knowledge, this is the first to report that left-sided CRCs show significantly less frequent methylation at several loci and CpG island methylator phenotype (CIMP) than right-sided ones. BACKGROUND AND OBJECTIVES: MSI CRC occurs in 10-20% of unselected series of...

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PMID: 17786961
DOI: 10.1002/jso.20877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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