Article
Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice.
Autophagy - 1 Jan 2008
Kuma Akiko, Mizushima Noboru
Abstract excerpt
GFP-LC3 mice are widely used to monitor autophagy. Here, we report chromosomal mapping of the GFP.LC3 transgene in this mouse model. The transgene was located in a very distal region of chromosome 2, immediately upstream of a putative open reading frame that is thought to be a part of a pseudogene. With this information, we were able to generate a PCR system to easily determine zygosity. Homozygous GFP-LC3 mice...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
