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Article

Retroposition in a family of carcinoma-associated antigen genes.

1 Mar 1993

Abstract excerpt

The gene encoding the carcinoma-associated antigen defined by the monoclonal antibody GA733 is a member of a family of at least two type I membrane proteins. This study describes the mechanism of evolution of the GA733-1 and GA733-2 genes. A full-length cDNA clone for GA733-1 was obtained by screening a human placental library with a genomic DNA probe. Comparative analysis of the cDNA sequence with the previously...

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PMID: 8382772
DOI: 10.1128/mcb.13.3.1507

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