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Article

Inhibition of tumor angiogenesis by cell-permeable dominant negative SOX18 mutants.

Medical hypotheses - 1 Jan 2008

Luo Min, Guo Xiao-Tong, Yang Wei, Liu Liang-Qi, Li Li-Wen, Xin Xiao-Yan

Abstract excerpt

Angiogenesis play a key roles in tumor growth, invasion and metastasis, and has become an attractive target for anticancer drug development. Though a number of anti-angiogenic agents had entered clinical trials, few of them could reproduce the spectacular results in cancer patients as that had been seen in pre-clinical tumor models. Therefore, exploring novel anti-angiogenic agents is highly deserved. SOX18, a...

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Share to Endothelium
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Share to High Mobility Group Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to SOXF Transcription Factors

Share to Vascular Cell Adhesion Molecule-1

Source

Identifiers

PMID: 17768012
DOI: 10.1016/j.mehy.2007.07.024

Genes

SOX18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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