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Article

VEGFD regulates blood vascular development by modulating SOX18 activity

23 Nov 2013

Abstract excerpt

Vascular endothelial growth factor-D (VEGFD) is a potent pro-lymphangiogenic molecule during tumor growth and is considered a key therapeutic target to modulate metastasis. Despite roles in pathological neo-lymphangiogenesis, the characterization of an endogenous role for VEGFD in vascular development has remained elusive. Here, we used zebrafish to assay for genetic interactions between the Vegf/Vegf-receptor...

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Identifiers

PMID: 24269955
DOI: 10.1182/blood-2013-04-495432

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