Article
SOX18 directly interacts with MEF2C in endothelial cells.
Biochemical and biophysical research communications - 21 Sept 2001
Hosking B M, Wang S C, Chen S L, Penning S, Koopman P, Muscat G E
Abstract excerpt
Recently, we demonstrated that mutations in the Sry-related HMG box gene Sox18 underlie vascular and hair follicle defects in the mouse allelic mutants ragged (Ra) and RaJ. Ra mice display numerous anomalies in the homozygote including, oedema, peritoneal secretions, and are almost completely naked. Sox18 and the MADS box transcription factor, Mef2C, are expressed in developing endothelial cells. Null mutants in...
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