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Article

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos.

Biochemical and biophysical research communications - 31 Aug 2007

Sakamoto Youhei, Hara Kenshiro, Kanai-Azuma Masami, Matsui Toshiyasu, Miura Yutaroh, Tsunekawa Naoki, Kurohmaru Masamichi, Saijoh Yukio, Koopman Peter, Kanai Yoshiakira

Abstract excerpt

Sox7, -17 and -18 constitute the Sox subgroup F (SoxF) of HMG box transcription factor genes, which all are co-expressed in developing vascular endothelial cells in mice. Here we characterized cardiovascular phenotypes of Sox17/Sox18-double and Sox17-single null embryos during early-somite stages. Whole-mount PECAM staining demonstrated the aberrant heart looping, enlarged cardinal vein and mild defects in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17610846
DOI: 10.1016/j.bbrc.2007.06.093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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