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Article

Differential signaling of dopamine-D2S and -D2L receptors to inhibit ERK1/2 phosphorylation.

Journal of neurochemistry - 1 Sept 2007

Van-Ham Irit Itzhaki, Banihashemi Behzad, Wilson Ariel M, Jacobsen Kirsten X, Czesak Margaret, Albert Paul R

Abstract excerpt

Although they have distinct functions, the signaling of dopamine-D(2) receptor short and long isoforms (D(2)S and D(2)L) is virtually identical. We compared inhibitory regulation of extracellular signal-regulated kinases (ERK1/2) in GH4 pituitary cells separately transfected with these isoforms. Activation of rat or human dopamine-D(2)S, muscarinic or somatostatin receptors inhibited thyrotropin-releasing...

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Identifiers

PMID: 17767702
DOI: 10.1111/j.1471-4159.2007.04650.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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