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Article

Conserved lysin and arginin residues in the extracellular loop of P2X(3) receptors are involved in agonist binding.

European journal of pharmacology - 8 Dec 2007

Fischer Wolfgang, Zadori Zoltan, Kullnick Yvonne, Gröger-Arndt Helke, Franke Heike, Wirkner Kerstin, Illes Peter, Mager Peter P

Abstract excerpt

Wild-type human (h) P2X(3) receptors expressed in HEK293 cells responded to the prototypic agonist alpha,beta-methylene ATP (alpha,beta-meATP) with rapidly desensitizing inward currents and an increase in the intracellular Ca(2+) concentration. In contrast to electrophysiological recordings, Ca(2+) microfluorimetry showed a lower maximum of the concentration-response curve of alpha,beta-meATP in the transiently...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17764672
DOI: 10.1016/j.ejphar.2007.07.068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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