Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An endocytic pathway as a target of tubby for regulation of fat storage.

EMBO reports - 1 Oct 2007

Mukhopadhyay Arnab, Pan Xiaojing, Lambright David G, Tissenbaum Heidi A

Abstract excerpt

The tubby loci provide a unique opportunity to study adult-onset obesity. Mutation in either mammalian tubby or its homologue in Caenorhabditis elegans, tub-1, results in increased fat storage. Previously, we have shown that TUB-1 interacts with a new Rab GTPase-activating protein, RBG-3, for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans Proteins
Share to Chemotaxis
Share to Endocytosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTPase-Activating Proteins

Share to rab GTP-Binding Proteins

Share to rab5 GTP-Binding Proteins

Share to rab7 GTP-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 17762880
DOI: 10.1038/sj.embor.7401055
PMCID: PMC2002550

Genes

TUB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17762880-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An endocytic pathway as a target of tubby for regulation of fat storage.PMID 17762880Read ↗

C. elegans tubby regulates life span and fat storage by two independent mechanisms.Semantic proximity Read ↗

Tubby proteins: the plot thickens.Semantic proximity Read ↗

Polygenic control of Caenorhabditis elegans fat storage.Semantic proximity Read ↗

The tubby-like proteins, a family with roles in neuronal development and function.Semantic proximity Read ↗

The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans.Semantic proximity Read ↗

TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth.Semantic proximity Read ↗

The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespan.Semantic proximity Read ↗

Rab32 is important for autophagy and lipid storage in Drosophila.Semantic proximity Read ↗

Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes.Semantic proximity Read ↗

The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespanSemantic proximity Read ↗

The JIP3 scaffold protein UNC-16 regulates RAB-5 dependent membrane trafficking at C. elegans synapses.Semantic proximity Read ↗

UNC-108/Rab2 regulates postendocytic trafficking in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.