Article
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes.
Nature - 16 Jan 2003
Ashrafi Kaveh, Chang Francesca Y, Watts Jennifer L, Fraser Andrew G, Kamath Ravi S, Ahringer Julie, Ruvkun Gary
Abstract excerpt
Regulation of body fat storage involves signalling between centres that regulate feeding in the brain and sites of fat storage and use in the body. Here we describe an assay for analysing fat storage and mobilization in living Caenorhabditis elegans. By using RNA-mediated interference (RNAi) to d...
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