Article
Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules.
Molecular and cellular biology - 1 Sept 2002
Riedel Dietmar, Antonin Wolfram, Fernandez-Chacon Rafael, Alvarez de Toledo Guillermo, Jo Tobias, Geppert Martin, Valentijn Jack A, Valentijn Karin, Jamieson James D, Südhof Thomas C, Jahn Reinhard
Abstract excerpt
Rab3D, a member of the Rab3 subfamily of the Rab/ypt GTPases, is expressed on zymogen granules in the pancreas as well as on secretory vesicles in mast cells and in the parotid gland. To shed light on the function of Rab3D, we have generated Rab3D-deficient mice. These mice are viable and have no...
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