Polymorphism of the alleles of the merozoite surface antigens MSA1 and MSA2 in Plasmodium falciparum wild isolates from Colombia.

doi:10.1016/0166-6851(91)90070-m

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Article

Polymorphism of the alleles of the merozoite surface antigens MSA1 and MSA2 in Plasmodium falciparum wild isolates from Colombia.

Molecular and biochemical parasitology - 1 Dec 1991

Snewin V A, Herrera M, Sanchez G, Scherf A, Langsley G, Herrera S

Abstract excerpt

The degree of polymorphism and the allelic distribution of 2 major Plasmodium falciparum merozoite surface antigens (MSA1 and MSA2) have been analysed in clinical isolates from Colombia. DNA was prepared directly from patients' blood and used in PCR reactions to amplify block 2 of MSA1 and the central region from MSA2. Thirty one samples were analysed and a marked degree of length polymorphism was detected,...

Topics

Adolescent
Adult
Alleles
Animals
Antigens, Protozoan
Antigens, Surface
Base Sequence
Child
Cloning, Molecular
DNA, Protozoan
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Malaria, Falciparum

Male

Merozoite Surface Protein 1

Middle Aged

Molecular Sequence Data

Plasmodium falciparum

Source

Open in PubMed

Identifiers

PMID: 1775170
DOI: 10.1016/0166-6851(91)90070-m

Genes

CAMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1775170-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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