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Article

Structural diversity in the Plasmodium falciparum merozoite surface antigen 2.

Proceedings of the National Academy of Sciences of the United States of America - 1 Mar 1991

Smythe J A, Coppel R L, Day K P, Martin R K, Oduola A M, Kemp D J, Anders R F

Abstract excerpt

Antigens associated with the surface of merozoites of the malaria parasite Plasmodium falciparum are directly accessible to immune attack and therefore are prime vaccine candidates. We have previously shown that one of the two known merozoite surface antigens (merozoite surface antigen 2; MSA-2) exhibits considerable sequence and antigenic diversity in different isolates. The sequences of MSA-2 from three...

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Identifiers

PMID: 2000383
DOI: 10.1073/pnas.88.5.1751
PMCID: PMC51102

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