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Article

Roles and regulation of the cardiac sodium channel Na v 1.5: recent insights from experimental studies.

Cardiovascular research - 1 Dec 2007

Abriel Hugues

Abstract excerpt

During the past decade, Na(v)1.5, the main voltage-gated Na(+) channel in the heart, has been shown to be involved in many cardiac diseases. Genetic variants in the gene SCN5A, encoding Na(v)1.5, have been linked to various cardiac phenotypes, such as the congenital and acquired long QT syndromes, Brugada syndrome, conduction slowing, sick sinus syndrome, atrial fibrillation, and even cases of dilated...

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Identifiers

PMID: 17727828
DOI: 10.1016/j.cardiores.2007.07.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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