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Article

Mouse models of SCN5A-related cardiac arrhythmias.

Progress in biophysics and molecular biology - 1 Jan 2000

Charpentier Flavien, Bourgé Anne, Mérot Jean

Abstract excerpt

Both gain- and loss-of-function mutations in the SCN5A gene, which encodes the alpha-subunit of the cardiac voltage-gated Na+ channel Na(v)1.5, are well established to underlie hereditary arrhythmic syndromes (cardiac channelopathies) such as the type 3 long QT syndrome, cardiac conduction diseases, Brugada syndrome, sick sinus syndrome, atrial standstill and numerous overlap syndromes. Although patch-clamp...

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Source

Identifiers

PMID: 19041666
DOI: 10.1016/j.pbiomolbio.2008.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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