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Article

Low somatic K-ras mutation frequency in colorectal cancer diagnosed under the age of 45 years.

European journal of cancer (Oxford, England : 1990) - 1 Jul 2006

Alsop Kathryn, Mead Leeanne, Smith Letitia D, Royce Simon G, Tesoriero Andrea A, Young Joanne P, Haydon Andrew, Grubb Garry, Giles Graham G, Jenkins Mark A, Hopper John L, Southey Melissa C

Abstract excerpt

Somatic mutation of K-ras is known to be a common event in colorectal cancer tumourigenesis however its association with age at onset has not been widely explored. In this study, we have analyzed tumours from a population-based study of colorectal cancer diagnosed before the age of 45 years, in which cases had been previously screened for germ-line mismatch repair gene mutations and for microsatellite...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16765042
DOI: 10.1016/j.ejca.2006.02.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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