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Article

Patterns of selection in anti-malarial immune genes in malaria vectors: evidence for adaptive evolution in LRIM1 in Anopheles arabiensis.

PloS one - 29 Aug 2007

Slotman Michel A, Parmakelis Aristeidis, Marshall Jonathon C, Awono-Ambene Parfait H, Antonio-Nkondjo Christophe, Simard Frederic, Caccone Adalgisa, Powell Jeffrey R

Abstract excerpt

BACKGROUND: Co-evolution between Plasmodium species and its vectors may result in adaptive changes in genes that are crucial components of the vector's defense against the pathogen. By analyzing which genes show evidence of positive selection in malaria vectors, but not in closely related non-vectors, we can identify genes that are crucial for the mosquito's resistance against Plasmodium. METHODOLOGY/PRINCIPLE...

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PMID: 17726523
DOI: 10.1371/journal.pone.0000793
PMCID: PMC1945087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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