Article
Polymorphisms in Anopheles gambiae immune genes associated with natural resistance to Plasmodium falciparum.
PLoS pathogens - 16 Sept 2010
Harris Caroline, Lambrechts Louis, Rousset François, Abate Luc, Nsango Sandrine E, Fontenille Didier, Morlais Isabelle, Cohuet Anna
Abstract excerpt
Many genes involved in the immune response of Anopheles gambiae, the main malaria vector in Africa, have been identified, but whether naturally occurring polymorphisms in these genes underlie variation in resistance to the human malaria parasite, Plasmodium falciparum, is currently unknown. Here we carried out a candidate gene association study to identify single nucleotide polymorphisms (SNPs) associated with...
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