Article
Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgery.
Anesthesiology - 1 Sept 2007
Leung Jacqueline M, Sands Laura P, Wang Yun, Poon Annie, Kwok Pui-yan, Kane John P, Pullinger Clive R
Abstract excerpt
BACKGROUND: Whether patients who subsequently develop early postoperative delirium have a genetic predisposition that renders them at risk for postoperative delirium has not been determined. METHODS: The authors conducted a nested cohort study to include patients aged > or = 65 yr who were scheduled to undergo major noncardiac surgery requiring anesthesia. A structured interview was conducted preoperatively and...
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