Article
The association between delirium and the apolipoprotein E epsilon4 allele in the elderly.
Psychiatric genetics - 1 Oct 2007
van Munster Barbara C, Korevaar Johanna C, de Rooij Sophia E, Levi Marcel, Zwinderman Aeilko H
Abstract excerpt
OBJECTIVE: As not all patients with similar risk factors and eliciting conditions develop delirium; it may be hypothesized that genetic variation may play a role in the risk of delirium. On the basis of the relationship between dementia, respectively reduced cholinergic activity, and the APOE epsilon4-allele, and the similarities between dementia and delirium in reduced cholinergic activity, the APOE...
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