Article
Genetic Contributors to Postoperative Delirium and Their Implications for Dementia Outcomes.
Anesthesiology - 1 Oct 2026
Ding Kewen, Wei Xiaojin, Tao Yifei, Chen Sihan, Zhang Changteng, Chen Runfu, Chen Hai, Han Xikun, Song Jiangning, Liu Jin, Zhang Shu, Chen Chan
Abstract excerpt
BACKGROUND: Postoperative delirium (POD) is a perioperative neurocognitive disorder that substantially impairs patient recovery. Unfortunately, its genetic risk profile and relationship with subsequent dementia remain unclear. This study aimed to elucidate genetic contributors to POD identified via Hospital Episode Statistics codes and to examine its association with subsequent dementia. METHODS: The study...
Read the complete abstract on PubMedTopics
- Humans
- Dementia
- Genome-Wide Association Study
- Female
- Postoperative Complications
- Male