Article
Rhythm defects caused by newly engineered null mutations in Drosophila's cryptochrome gene.
Genetics - 1 Sept 2007
Dolezelova Eva, Dolezel David, Hall Jeffrey C
Abstract excerpt
Much of the knowledge about cryptochrome function in Drosophila stems from analyzing the cryb mutant. Several features of this variant's light responsiveness imply either that CRYb retains circadian-photoreceptive capacities or that additional CRY-independent light-input routes subserve these processes. Potentially to resolve these issues, we generated cry knock-out mutants (cry0's) by gene replacement. They...
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