Article
Advanced analysis of a cryptochrome mutation's effects on the robustness and phase of molecular cycles in isolated peripheral tissues of Drosophila.
BMC neuroscience - 15 Apr 2002
Levine Joel D, Funes Pablo, Dowse Harold B, Hall Jeffrey C
Abstract excerpt
BACKGROUND: Previously, we reported effects of the cry(b) mutation on circadian rhythms in period and timeless gene expression within isolated peripheral Drosophila tissues. We relied on luciferase activity driven by the respective regulatory genomic elements to provide real-time reporting of cycling gene expression. Subsequently, we developed a tool kit for the analysis of behavioral and molecular cycles. Here,...
Topics
- 5' Flanking Region
- Animals
- Circadian Rhythm
- Cryptochromes
- Drosophila Proteins
- Drosophila melanogaster
- Eye Proteins
- Flavoproteins
- Gene Expression Regulation
- Genes, Reporter
- Insect Proteins