Article
Drosophila cryb mutation reveals two circadian clocks that drive locomotor rhythm and have different responsiveness to light.
Journal of insect physiology - 1 Jun 2004
Yoshii Taishi, Funada Yuriko, Ibuki-Ishibashi Tadashi, Matsumoto Akira, Tanimura Teiichi, Tomioka Kenji
Abstract excerpt
Cryptochrome (CRY) is a blue-light-absorbing protein involved in the photic entrainment of the circadian clock in Drosophila melanogaster. We have investigated the locomotor activity rhythms of flies carrying cryb mutant and revealed that they have two separate circadian oscillators with different responsiveness to light. When kept in constant light conditions, wild-type flies became arrhythmic, while cryb mutant...
Topics
- Animals
- Animals, Genetically Modified
- Biological Clocks
- Circadian Rhythm
- Cryptochromes
- Drosophila Proteins
- Drosophila melanogaster
- Eye Proteins
- Gene Expression Regulation
- Immunohistochemistry
- Light
- Motor Activity
- Mutation
