PDFR and CRY signaling converge in a subset of clock neurons to modulate the amplitude and phase of circadian behavior in Drosophila.

Abstract excerpt

BACKGROUND: To synchronize their molecular rhythms, circadian pacemaker neurons must input both external and internal timing cues and, therefore, signal integration between sensory information and internal clock status is fundamental to normal circadian physiology. METHODOLOGY/PRINCIPAL FINDINGS: We demonstrate the specific convergence of clock-derived neuropeptide signaling with that of a deep brain...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Behavior, Animal
• Share to Biological Clocks
• Share to Circadian Rhythm