Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microarray Analysis of the Cellular Pathways Involved in the Adaptation to and Progression of Motor Neuron Injury in the SOD1 G93A Mouse Model of Familial ALS

22 Aug 2007

Abstract excerpt

The cellular pathways of motor neuronal injury have been investigated in the SOD1 G93A murine model of familial amyotrophic lateral sclerosis (ALS) using laser-capture microdissection and microarray analysis. The advantages of this study include the following: analysis of changes specifically in motor neurons (MNs), while still detecting effects of interactions with neighboring cells; the ability to profile...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to biodegradable polymer synthesis and properties
Share to Neurogenetic and Muscular Disorders Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17715356
DOI: 10.1523/jneurosci.1470-07.2007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microarray Analysis of the Cellular Pathways Involved in the Adaptation to and Progression of Motor Neuron Injury in the SOD1 G93A Mouse Model of Familial ALSPMID 17715356Read ↗

Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons.Semantic proximity Read ↗

Early gene expression changes in spinal cord from SOD1G93A Amyotrophic Lateral Sclerosis animal modelSemantic proximity Read ↗

Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.Semantic proximity Read ↗

Integrative gene-tissue microarray-based approach for identification of human disease biomarkers: application to amyotrophic lateral sclerosis.Semantic proximity Read ↗

Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS.Semantic proximity Read ↗

Differential gene expression in the axotomized facial motor nucleus of presymptomatic SOD1 mice.Semantic proximity Read ↗

Transcriptional profile of primary astrocytes expressing ALS‐linked mutant SOD1Semantic proximity Read ↗

No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse modelSemantic proximity Read ↗

Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.Semantic proximity Read ↗

RNA-Seq profiling of spinal cord motor neurons from a presymptomatic SOD1 ALS mouse.Semantic proximity Read ↗

Comparative Temporal Transcriptomic Analysis of SOD1 Mutations in iPSC-Motor NeuronsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.