Article
Early gene expression changes in spinal cord from SOD1G93A Amyotrophic Lateral Sclerosis animal model
1 Jan 2013
Abstract excerpt
Amyotrophic Lateral Sclerosis (ALS) is an adult-onset and fast progression neurodegenerative disease that leads to the loss of motor neurons. Mechanisms of selective motor neuron loss in ALS are unknown. The early events occurring in the spinal cord that may contribute to motor neuron death are not described, neither astrocytes participation in the pre-symptomatic phases of the disease. In order to identify ALS...
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